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  • Title: [Haemorrhagic oedema acute in neonatal skin. Immunological and ultrastructural examination (author's transl)].
    Author: Lambert D, Laurent R, Bouilly D, Saint-Mont C, Estavoyer JM, Agache P, Chapuis JL.
    Journal: Ann Dermatol Venereol; 1979 Dec; 106(12):975-87. PubMed ID: 533105.
    Abstract:
    There are three reports on acute haemorrhagic oedema of the skin of infants, an illness which English-speaking authors do not individualize but only regard as a clinical variety of Henoch-Schönlein purpura. Yet the features of the disease, as described in children under two years of age, are very characteristic. --Clinical feature is the sudden appearance of oedemas on face and limbs and of cocarde-like purpura with an occasional temperature. --Histological feature is the presence of leukocytoclastic vasculitis. --Immunologically the disease is characterized by the deposit of immune complexes. --Ultrastructural examination confirms the presence of leukocytoclastic vasculitis accompanied by deposit of immune complexes and of platelets. These three reports enable the authors to study the nosological aspects of the illness among the varieties of allergic vasculitis.
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