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  • Title: Effect of gene position on the timing of enzyme synthesis in synchronous cultures of yeast.
    Author: Tauro P, Halvorson HO.
    Journal: J Bacteriol; 1966 Sep; 92(3):652-61. PubMed ID: 5332081.
    Abstract:
    Tauro, Patric (The University of Wisconsin, Madison), and Harlyn O. Halvorson. Effect of gene position on the timing of enzyme synthesis in synchronous cultures of yeast. J. Bacteriol. 92:652-661.-In synchronously growing cultures of Saccharomyces cerevisiae, enzyme synthesis is periodic. The effect of various factors on the timing of alpha-glucosidase synthesis has been investigated. The period of the cell cycle during which alpha-glucosidase is synthesized is unaffected by the method employed to induce synchrony, as well as other environmental conditions. However, a definite relationship exists between the number of nonallelic structural genes present for alpha-glucosidase and the number of periods of synthesis during the cell cycle. It is concluded that the periodic synthesis of enzymes observed in synchronously growing cultures of yeast is probably the result of an ordered process of transcription of the various structural genes.
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