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  • Title: [Biliary lithiasis in cystic fibrosis. Study of the bile salts in the serum and in the bile in one case (author's transl)].
    Author: Feigelson J, Pécau Y, Bereziat G, Pépin D, Sauvegrain J, Pennaforte F, Roynette A.
    Journal: Nouv Presse Med; 1979 Oct 08; 8(38):3029-31. PubMed ID: 534165.
    Abstract:
    Biliary lithiasis was discovered in a girl aged 11 suffering from Cystic Fibrosis and who underwent partial small bowel resection for meconium ileus. A cholecystectomy was performed at 15. Examination of the stones showed that they were composed of cholesterol and chemical examination of the bile showed an increase of phospholipids and a decrease in bile salts. There was also a modification of the ratio (Formula: see text) in the serum and the bile. All those factors contribute to the insolubility of cholesterol and to the formation of lithiasis. For all those reasons, the authors recommend a regular radiologic surveillance of the gallbladder in Cystic Fibrosis.
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