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  • Title: Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.
    Author: Ueno Y, Ishikawa I.
    Journal: Appl Microbiol; 1969 Sep; 18(3):406-9. PubMed ID: 5373676.
    Abstract:
    Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of (14)C-labeled luteoskyrin was 2-(14)C-malonate.
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