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Title: The role of danazol in the management of precocious puberty. Author: Smith CS, Harris F. Journal: Postgrad Med J; 1979; 55 Suppl 5():81-6. PubMed ID: 537954. Abstract: The management, investigation and treatment of 12 children with precocious puberty is described. Danazol, a synthetic derivative of ethisterone, has been used over a period of 3 1/2 years. Its clinical, endocrine and biochemical effects have been evaluated. Danazol ha a very useful clinical effect in controlling the development of secondary sexual features but does not modify the rapid linear growth and skeletal maturity seen in this condition.[Abstract] [Full Text] [Related] [New Search]