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  • Title: Long-term treatment of ventricular arrhythmias with oral mexiletine.
    Author: Talbot RG, Julian DG, Prescott LF.
    Journal: Am Heart J; 1976 Jan; 91(1):58-65. PubMed ID: 53994.
    Abstract:
    Twenty-four patients with ventricular arrhythmias were treated with oral mexiletine for periods of from one to 16 months (total 10.4 patient-years). In 19 patients arrhythmias were satisfactorily controlled and plasma levels previously shown to be within the therapeutic range were maintained on an 8 hourly regimen. The drug was well tolerated in most patients and regular hematological and biochemical screening revealed no problems of toxicity.
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