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  • Title: [Suppressive factor release by mouse lymphocytes after incubation with syngeneic erythrocytes].
    Author: Leskov VP, Cheredeev AN, Solov'ev VV.
    Journal: Biull Eksp Biol Med; 1979 Nov; 88(11):576-8. PubMed ID: 540151.
    Abstract:
    Suppressive factor, inhibiting the immune response to sheep red blood cells, is released after incubation in vitro of spleen cells of (CBA X C57BL) F1 mice, immunized with rat erythrocytes, in contact with syngeneic erythrocytes. Intravenous immunization results in the factor release by thymus and/or spleen cells but not by the bone marrow or lymph node cells. It is suggested that the factor is not antigen-specific and is secreted by non-specific T cells suppressors after the contact with syngeneic erythrocytes.
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