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  • Title: Studies on the pathogenesis of fever. XVII. The cationic control of pyrogen release from exudate granulocytes in vitro.
    Author: Hahn HH, Cheuk SF, Moore DM, Wood WB.
    Journal: J Exp Med; 1970 Jan 01; 131(1):165-78. PubMed ID: 5409945.
    Abstract:
    Evidence has been presented that the release of active endogenous pyrogen from rabbit exudate granulocytes incubated in isotonic NaCl is a relatively prompt energy-dependent process that is preceded by a rise in intracellular pyrogen, and involves a rise in total intracellular cations and an increased permeability of the cell membranes, but does not require the synthesis of new proteins.
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