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  • Title: Habituation and dishabituation of the gill-withdrawal reflex in Aplysia.
    Author: Pinsker H, Kupfermann I, Castellucci V, Kandel E.
    Journal: Science; 1970 Mar 27; 167(3926):1740-2. PubMed ID: 5416541.
    Abstract:
    A behavioral reflex mediated by identified motor neurons in the abdominal ganglion of Aplysia undergoes two simple forms of shortterm modification. When the gill-with-drawal reflex was repeatedly evoked by a tactile stimulus to the siphon or mantle shelf, the amplitude of the response showed marked decrement (habituation). After a period of rest the response showed spontaneous recovery. The amplitude of a habituated response was facilitated by the presentation of a strong tactile stimulus to another part of the animal (dishabituation). Many characteristics of habituation and dishabituation in Aplysia are similar to those in vertebrates.
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