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  • Title: Regional lung function in patients with obstructive lung diseases.
    Author: Gaziano D, Seaton A, Ogilvie C.
    Journal: Br Med J; 1970 May 09; 2(5705):330-3. PubMed ID: 5429452.
    Abstract:
    Regional lung function was measured, using radioactive xenon-133, in a group of normal subjects and in three carefully defined groups of patients with obstructive lung disease. When compared with the normal subjects, patients in the emphysematous group showed a relative reduction of ventilation and perfusion to the upper zones, while patients having chronic bronchitis without cardiac or respiratory failure showed a predominantly lower zone defect. In the group of patients with chronic bronchitis with cardiac and respiratory failure no consistent pattern was found.
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