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  • Title: Comparison of the acetylation of proteins and nucleic acids.
    Author: Paik WK, Kim S.
    Journal: Biochem J; 1970 Feb; 116(4):611-5. PubMed ID: 5435491.
    Abstract:
    The possibility of acetylation of nucleic acids was examined. Although protein is actively acetylated with [1-(14)C]acetic acid in rat liver systems in vivo and in vitro and in a frog liver system in vivo, nucleic acids are not acetylated under these conditions; nucleic acids purified from these sources are without radioactivity. Requirements for acetylation in vitro of protein in rat liver are different from those in frog liver; GSH has no effect in the rat liver system and is inhibitory in the frog liver system. Among various acetylated proteins, proteins insoluble in 0.1m-sulphuric acid have the highest radioactivity.
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