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  • Title: Hormone-sensitive adenyl cyclase: cytochemical localization in rat liver.
    Author: Reik L, Petzold GL, Higgins JA, Greengard P, Barrnett RJ.
    Journal: Science; 1970 Apr 17; 168(3929):382-4. PubMed ID: 5435897.
    Abstract:
    An electron microscopic procedure has been developed, using rat liver, for the localization of hormone-sensitive adenyl cyclase. Isoproterenol-sensitive adenyl cyclase is located almost exclusively in the parenchymal cells. In contrast, glucagon-sensitive adenyl cyclase is located primarily in the reticulo-endothelial cells but is also present in parenchymal cells. Sodium fluoride-sensitive adenyl cyclase is found in both cell types.
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