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  • Title: Intestinal hydrolysis and conjugation of a pesticidal carbamate in vitro.
    Author: Pekas JC, Paulson GD.
    Journal: Science; 1970 Oct 02; 170(3953):77-8. PubMed ID: 5452894.
    Abstract:
    The metabolite 1-[1-(14)C]naphthyl glucuronide was isolated from mucosal and serosal fluids of everted sacs of rat small intestine incubated in media containing either the insecticide 1-[1-(14)C]naphthyl N-methylcarbamate (carbaryl) or 1-[1-(14)C]naphthol. The hydrolysis of carbaryl and conjugation of the liberated naphthol indicated some degree of metabolism by the intestine before absorption.
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