These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Inhibition of nucleic acid and protein synthesis mouse spleen cells in vitro by azathioprine.
    Author: Chan GY, Stone RL.
    Journal: Appl Microbiol; 1970 Dec; 20(6):910-2. PubMed ID: 5492440.
    Abstract:
    The effect of azathioprine on macromolecular biosynthesis was studied in mouse spleen cells cultured in vitro. The rate of incorporation of (3)H-thymidine, (3)H-uridine, and (14)C-leucine into acid-insoluble material was used to measure deoxyribonucleic acid, ribonucleic acid, and protein synthesis. Results indicate that azathioprine inhibited nucleic acid and protein synthesis at levels which did not decrease cell viability.
    [Abstract] [Full Text] [Related] [New Search]