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  • Title: [Alpha-thalassemia in Puglia. II. Neonatal screening for Bart's hemoglobin].
    Author: Izzo P, Pasculli D, Schonauer S, Mudoni A, De Mattia D, Constantino R, Melpignano A, Saccia M.
    Journal: Boll Soc Ital Biol Sper; 1979 Apr 15; 55(7):703-8. PubMed ID: 550897.
    Abstract:
    550 blood specimens from the umbilical cord of newborn babies from Apulia have been screened in order to detect Hb Bart's. The electrophoresis of the haemoglobin by Cellogel (Tris Glycine pH 8.6) carried out on the 550 specimens have revealed in 43 variable quantities of Hb Bart's: 34 cases (6,18%) showed non measurable quota, whereas in the other 9 cases (1,63%) Hb Bart's varied from 2,19% to 26%. The haemoglobin biosynthesis "in vitro" of the baby presenting 26% of Hb Bart's has been reported.
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