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  • Title: [OEstradiol and progesterone steroid hormone receptors in cancer of the endometrium. The significance of the progesterone receptor (author's transl)].
    Author: Martin PM, Rolland PH, Gammerre M, Serment H.
    Journal: J Gynecol Obstet Biol Reprod (Paris); 1979; 8(8):681-4. PubMed ID: 553927.
    Abstract:
    It would seem that the satisfactory way for the clinician to orientate the treatment by hormones in cancers of the endometrium lies in the presence at the same time of oestrogen and progesterone receptors and in particular of the latter. This applies when treating cancers of the endometrium with hormones in a way that is directed by chemical determination of hormone susceptibility. This study investigates the frequency of the presence of estrogen and progesterone receptors in the different anatomopathological types of endometrial cancer. The study has been conducted on cancerous tissues samples before and after hormonotherapy. From a clinical point of view it is very important to know that, at least apparently, the best results are obtained when both estrogen and progesterone receptors are present in the cancerous tissues.
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