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  • Title: ["Low triiodothyronine (T3) syndrome": "thyroxine (T4) euthyroidism" evidence (author's transl)].
    Author: Wémeau JL, Lefebvre J, Linquette M.
    Journal: Nouv Presse Med; 1979 Feb 03; 8(6):415-9. PubMed ID: 554102.
    Abstract:
    As first described in serious systemic illnesses isolated decreased T3 plasma concentration was related to impaired peripheral conversion of T4, to T3 with preferential production of reverse T3 (rT3). A "low T3 syndrome" was seen in 47 out of 109 patients with extra-thyroidal diseases. Metabolic state, TSH and TSH responses to TRH were normal despite of low T3 concentration. Euthyroidism seems mainly due to T4 itself in these patients.
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