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  • Title: [Variations in the urinary level of MHPG in depressive syndromes].
    Author: Loeb C, Roccatagliatà G, Besio G.
    Journal: Schweiz Arch Neurol Neurochir Psychiatr; 1979; 125(2):337-48. PubMed ID: 555549.
    Abstract:
    MPHG urinary changes were investigated in a group of patients affected by different forms of depressive illness. No significant difference was noticed depending on age, diagnosis, number and duration of episodes. Considering the group as a whole, a significant increase of MHPG urinary levels was noted after the recovery, although the patients received different drugs (Tricyclic + phenothiazine, Trazodone, IMAO). Specifically, the patients treated with IMAO and Trazodone, either recovered or ameliorated, showed a remarkable increase of MHPG urinary levels, whereas a decrease was noticed in the group who was administered tricyclic antidepressants.
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