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  • Title: Alternative pathways for DNA-thymine synthesis in stimulated leucocytes.
    Author: Wolberg WH.
    Journal: Clin Exp Immunol; 1971 Feb; 8(2):177-86. PubMed ID: 5573423.
    Abstract:
    In vitro transformation of stimulated lymphocytes is frequently evaluated from their ability to incorporate thymidine. This technique measures only one pathway by which cells synthesize DNA-thymine. The purpose of this study was to evaluate the incorporation of various precursors into the DNA-thymine of stimulated leucocytes. It was found that the uptake of thymidine did provide an adequate assessment of total precursor incorporation.
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