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  • Title: Synthesis of 5S and 4S RNA in metaphase-arrested HeLa cells.
    Author: Zylber EA, Penman S.
    Journal: Science; 1971 May 28; 172(3986):947-9. PubMed ID: 5573566.
    Abstract:
    The continued synthesis of both 5S and 4S RNA in metaphase-arrested HeLa cells is demonstrated; 5S RNA is apparently synthesized at approximately 74 percent of the interphase rate, while 4S RNA is synthesized at approximately one-third the rate. The ratio of uridine incorporation to RNA methylation is used to correct for the alteration in the specific activity of the pyrimidine pool during metaphase arrest.
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