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  • Title: Plasma beta-subunit human chorionic gonadotropin assay in molar pregnancy and choriocarcinoma.
    Author: Yuen BH, Cannon W, Benedet JL, Boyes DA.
    Journal: Am J Obstet Gynecol; 1977 Apr 01; 127(7):711-2. PubMed ID: 557901.
    Abstract:
    Serum plasma levels of the beta-subunit of human chorionic gonadotropin (HCG-beta) were measured by radioimmunoassay in 24 women with molar pregnancies and five with choriocarcinoma. In the patients with molar pregnancy, plasma HCG-beta concentrations became undetectable within 8 to 173 days. In the patients with choriocarcinoma, plasma HCG-beta levels declined rapidly with appropriate chemotherapy. Serial plasma HCG-beta assay in this series accurately determined remission and detected early recurrences during follow-up. All patients are in remission with a mean follow-up of 22 months for the patients with choriocarcinoma.
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