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  • Title: [Regulation of the total functional state of the brain in dogs in the presence of the 1st and repeated increases in total illumination].
    Author: Meshcheriakov VA, Golikov IuP.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1977; 27(3):466-70. PubMed ID: 561491.
    Abstract:
    The influence of the first and repeated increases of total illumination of the experimental chamber on conditioned activity was studied in chronic experiments on six dogs by the secretory alimentary conditioned reflex method. It was found that such repeated functional loads exert a training effect on the mechanism regulating the general functional state of the brain. In preliminarily trained animals different components of the conditioned reflex are rapidly and synchronously reorganized. In non-trained animals the reorganization of the brain general functional state was prolonged and accompanied by development of a pronounced emotional stress. It has been assumed that training of the functions controlling the general functional state of the brain is based on conditioned mechanisms. An important part is played by the mechanism of conditioned inhibition, which prevents a prolonged retention and reproduction of an excessively intensive level of emotional stress.
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