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  • Title: Respiratory syncytial virus isolation by combined continuous flow-isopycnic banding centrifugation.
    Author: Cline GB, Coates H, Anderson NG, Chanock RM, Harris WW.
    Journal: J Virol; 1967 Aug; 1(4):659-64. PubMed ID: 5621468.
    Abstract:
    A new zonal centrifuge rotor (B-IX) which combines continuous sample flow centrifugation with isopycnic banding has been used to isolate and concentrate respiratory syncytial virus from liter volumes of culture fluid. This isolation technique utilizes a sucrose density gradient to trap and isopycnically band the virus particles, and permits recovery of the particles from the rotor in an unaggregated condition.
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