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  • Title: Hydrocortisone requirement for the induction of glutamine synthetase in chick-embryo retinas.
    Author: Reif-Lehrer L, Amos H.
    Journal: Biochem J; 1968 Jan; 106(2):425-30. PubMed ID: 5637352.
    Abstract:
    Hydrocortisone has been found to induce glutamine synthetase activity in chick-embryo retinas in culture. Evidence is presented to show that the hydrocortisone is definitely required for transcription; its requirement for translation has not been ruled out. The possible identity of hydrocortisone with an active component of calf-serum diffusate reported earlier is discussed. The data also indicate that the glutamine synthetase messenger RNA is stable for at least several hours.
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