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  • Title: Regulation of pentitol metabolism by Aerobacter aerogenes. I. Coordinate control of ribitol dehydrogenase and D-ribulokinase activities.
    Author: Bisson TM, Mortlock RP.
    Journal: J Bacteriol; 1968 Mar; 95(3):925-31. PubMed ID: 5643065.
    Abstract:
    Induction studies on Aerobacter aerogenes strain PRL-R3, using ribitol as the inducer-substrate, indicated that two enzymes of ribitol catabolism, ribitol dehydrogenase and d-ribulokinase, are coordinately induced. The utilization of d-arabinose as a substrate resulted in the induction of ribitol dehydrogenase as well as d-ribulokinase. Mutants which were constitutive for ribitol dehydrogenase were also constitutive for d-ribulokinase. In contrast, d-xylulokinase and d-arabitol dehydrogenase did not appear to be coordinately controlled. Induction studies and examination of d-arabitol dehydrogenase constitutive mutants indicated that the three enzymes of the converging pathways for d-arabitol and d-xylose catabolism are under separate control.
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