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  • Title: [Splenectomy in idiopathic thrombocytopenic purpura: short- and long-term results (author's transl)].
    Author: Francesconi M, Domanig E, Lechner K, Niessner H, Nowotny C, Thaler E.
    Journal: Wien Klin Wochenschr; 1978 Mar 31; 90(7):233-6. PubMed ID: 565104.
    Abstract:
    The results of splenectomy in 25 patients with chronic idiopathic thrombocytopenic purpura (ITP) are reported. Splenectomy was performed when the platelet count was consistently less than 30,000/mm3 in spite of glucocorticoid therapy over an observation period of at least six months. Following splenectomy, 13 patients showed complete remission, 9 partial remission, whilst in 3 cases the condition was unaffected by splenectomy. It is not possible to predict a successful response to splenectomy on the basis of preoperative laboratory findings. A rise in thrombocyte count to over 400,000/mm3 during the first 2 weeks after splenectomy makes complete remission very likely.
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