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  • Title: Influence of treatment duration on audiogenic seizure susceptibility during barbiturate withdrawal in rats.
    Author: McGee DH, Bourn WM.
    Journal: Experientia; 1978 Jul 15; 34(7):873-4. PubMed ID: 566673.
    Abstract:
    Barbiturate withdrawal seizure susceptibility in rats increased with increasing duration of treatment during a 15-day treatment period in which the animals were given an i.p. dose of sodium barbital every 12 h. This method of producing dependence has clear advantages over previously described methods.
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