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  • Title: Metachromatic leukodystrophy: diagnosis with samples of venous blood.
    Author: Percy AK, Brady RO.
    Journal: Science; 1968 Aug 09; 161(3841):594-5. PubMed ID: 5668537.
    Abstract:
    Arylsulfatase A and B have been demonstrated in preparations of human leukocytes. The level of activity of arylsulfatase A is markedly decreased in the preparations from patients with metachromatic leukodystrophy. Acid phosphatase and arylsulfatase B activities were normal. The assay of arylsulfatase A in leukocyte preparations can be useful in the diagnosis of metachromatic leukodystrophy while obviating the difficulties of current methods.
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