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  • Title: [Obstetrical problems in patients with Glanzmann's thrombasthenia. A casuistic presentation (author's transl)].
    Author: Heyes H, Scheck R, Rasche H.
    Journal: Geburtshilfe Frauenheilkd; 1979 Jan; 39(1):68-74. PubMed ID: 570532.
    Abstract:
    Glanzmann's thrombasthenia is a rare, autosomal recessive disorder of bleeding arrest. The differential diagnosis of this platelet defect with respect to recently gained knowledge is presented in the case of a pregnant woman. Because of pelvic presentation a cesarean section was performed after adequate platelet substitution, which did not involve excessive blood loss. A severe puerperal infection necessitated an abdominal hysterectomy after appropriate platelet transfusion. The difficulties in testing platelet function in the newborn are discussed. The effectiveness of a commercially available homologous phospholipide complex (Fibraccel) was tested on the patient in a noncritical phase. The results appear important for general procedure when pregnancy and platelet dysfunction concur.
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