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  • Title: Involvement of cytoskeletal structures in nerve-growth-factor-mediated induction of ornithine decarboxylase.
    Author: Lakshmanan J.
    Journal: Biochem J; 1979 Jan 15; 178(1):245-8. PubMed ID: 571277.
    Abstract:
    Induction of ornithine decarboxylase elicited in response to nerve-growth factor in target organs is greatly decreased by preincubation of these tissues with cytoskeletal poisons such as vinblastine, diamide, cytochalasin B and colchicine. These results are interpreted as evidence for the involvement of receptor-associated cytoskeletal structures in mediating the nerve-growth-factor-specific induction of ornithine decarboxylase.
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