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  • Title: A histone programme during the life cycle of the sea urchin.
    Author: Brandt WF, Strickland WN, Strickland M, Carlisle L, Woods D, von Holt C.
    Journal: Eur J Biochem; 1979 Feb 15; 94(1):1-10. PubMed ID: 571333.
    Abstract:
    The histone complement of chromatin from early gastrula, late gastrula and from fully differentiated gut cells of the sea urchin Parechinus angulosus has been fractionated by molecular sieve and ion-exchange chromatography. Several of the subfractions thus isolated have been characterized by amino acid composition and partial amino acid sequences as a series of variants of the histones H1, H2A and H2B. Specific histone variants are present in chromatin at specific stages of differentiation.
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