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  • Title: Employment of bis-intercalating dyes for the "in situ" study of DNA composition.
    Author: Bottiroli G, Giordano P, Doglia S, Cionini PG.
    Journal: Basic Appl Histochem; 1979; 23(1):59-63. PubMed ID: 574384.
    Abstract:
    Spectrofluorometric characteristics of DNA-RO4 complexes have been studied in order to evaluate the possibility of employment of RO4 (a bis-intercalating dye) for the determination of the DNA base composition. The results have shown the usefulness of this compound for DNA with AT percentage between 30% and 60%. RO4 has been also applied to the study of the chromosome banding mechanism.
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