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  • Title: Immunoelectrophoretic studies on the kinetics of plasmic degradation of human fibrinogen.
    Author: Braude R, Altman R, Rouvier J, Aguilar N.
    Journal: Thromb Haemost; 1977 Feb 28; 37(1):136-43. PubMed ID: 576511.
    Abstract:
    In vitro degradation of fibrinogen results in the appearance of an early fragment, different in its electrophoretic mobility to that of fragments X, Y, D and E. It reacts with antifibrinogen antiserum does not react with anti-D antiserum and it is antigenically related to fragment E. Compared with terminal fragment E, it migrates more slowly towards the anode, it appears earlier and in a greater concentration at the beginning, decreasing and disappearing during degradation. The antigen antibody crossed electrophoresis was used in these experiments, but to distinguish the fragments from already known X, Y or even fibrinogen, the applying of an intermediate gel with anti D was of great value.
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