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  • Title: Five cases of absence of iodide concentrating mechanism.
    Author: Toyoshima K, Matsumoto Y, Nishida M, Yabuuchi H.
    Journal: Acta Endocrinol (Copenh); 1977 Mar; 84(3):527-37. PubMed ID: 576528.
    Abstract:
    Five cases, 2 males and 3 females, with absence of iodide concentrating mechanism are reported. Three of the five subjects are siblings and the eldest sister has no symptom to account for the cretinism. All 5 cases have improved clinically following the administration of potassium iodide and 4 cases are still in a euthyroid state without any adverse effects during a half to more than 4 years. This study suggests that the absence of iodide concentrating mechanism might be erroneously diagnosed as athyroidal cretinism or adolescent non-toxic diffuse goitre, and may at times not show any clinical symptoms.
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