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  • Title: Luteinizing hormone: action on the graafian follicle in vitro.
    Author: Keyes PL.
    Journal: Science; 1969 May 16; 164(3881):846-7. PubMed ID: 5767789.
    Abstract:
    Graafian follicles, dissected intact from the rabbit ovary and incubated for 40 minutes with luteinizing hormone, developed into corpora lutea when autotransplanted under the kidney capsule. Follicles incubated with follicle-stimulating hormone or without hormone degenerated and failed to luteinize. Direct exposure of the mammalian follicle to luteinizing hormone initiates luteinization and formation of the corpus luteum.
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