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  • Title: Aspirin- and bile- induced acute erosive gastritis: its prevention by metiamide therapy.
    Author: Mann NS, Sachdev AJ.
    Journal: Arch Pathol Lab Med; 1977 Apr; 101(4):206-7. PubMed ID: 576788.
    Abstract:
    Aspirin or bile administered by esophageal intubation to rats produced acute gastric erosions. These injuries could have been prevented by the prior administration by esophageal intubation of metiamide, a histamine H2 receptor antagonist that is known to inhibit gastric acid secretion.
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