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  • Title: Antigen-antibody studies in the ABO blood group system with particular reference to cross-reacting antibodies in group O sera.
    Author: Lincoln PJ, Dodd BE.
    Journal: Immunology; 1969 Mar; 16(3):301-10. PubMed ID: 5770382.
    Abstract:
    A comparison has been made between the reactivity of cross-reacting antibody from group O sera titrated against A cells and the reactivity when titrated against cells of group B. It is considered that the experimental findings require the postulation that cross-reacting antibodies which are produced in response to stimulation by antigen A have a different configuration from those produced in response to antigen B. The results also suggest that elution of antibody from cells at 56° may cause minor changes in spatial configuraiton which diminish the ability of some antibodies to combine with some subgroups of the A system.
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