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  • Title: Florid epithelioid cell and sarcoid-type reaction associated with non-Hodgkin's lymphoma.
    Author: Kahn LB, King H, Jacobs P.
    Journal: S Afr Med J; 1977 Mar 12; 51(11):341-7. PubMed ID: 577052.
    Abstract:
    Five patients suffering from non-Hodgkin's lymphoma associated with an intense infiltration of epithelioid histiocytes and even sarcoid-type granulomas in the involved tissue are described. A similar tissue reaction, at both involved and uninvolved sites, has been described in patients with Hodgkin's disease. The cause of this reaction may be immunological; its prognostic significance still awaits elucidation. In the case of non-Hodgkin's lymphomas, it may cause difficulty in diagnosis of lymphoma and hence may result in unnecessary delay in the initiation of therapy.
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