These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Angiotensin II inhibition. Treatment of congestive cardiac failure in a high-renin hypertension.
    Author: Gavras H, Flessas A, Ryan TJ, Brunner HR, Faxon DP, Gavras I.
    Journal: JAMA; 1977 Aug 22; 238(8):880-2. PubMed ID: 577978.
    Abstract:
    A patient with intractable congestive cardiac failure secondary to renovascular hypertension and severe coronary artery disease was infused with the competitive antagonist of angiotensin II, saralasin acetate. The infusion produced an impressive increase in cardiac output and left ventricular stroke work index in parallel with a striking decrease in the systemic and pulmonary vascular resistance, the coronary resistance, and the myocardial oxygen consumption. It is suggested that angiotensin inhibition may present advantages over other forms of treatment of congestive cardiac failure in selected cases.
    [Abstract] [Full Text] [Related] [New Search]