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  • Title: Amniotic fluid shake test versus lecithin-sphingomyelin ratio in the antenatal prediction of respiratory distress syndrome.
    Author: Szabó IM, Csaba IF, Drozgyik IA, Novák PF.
    Journal: Z Geburtshilfe Perinatol; 1977 Aug; 181(4):260-3. PubMed ID: 578601.
    Abstract:
    Surfactant content of 211 amniotic fluid samples raken between 28 and 42 weeks' gestations was determined by the shake test. Parallel with this also the lecithin/sphingomyelin (L/S) ratio was measured in 99 cases. When the test was positive no respiratory distress syndrome (RDS) occurred, while 25 RDS (53.34%) developed in 46 newborns with negative test and 8 RDS (15.38%) in 52 newborns with intermediate test. RDS was observed in all cases when the L/S ratio was below 1.5. At L/S ratios between 1.5 and 2.0, RDS appeared in 50% of the negative tests and 20% of the intermediate tests. However, when the L/S ratio was over 2.0 no RDS occured even in the case of negative tests. For the clinical praxis the positive test gives an exact information; no RDS is to be expected in such cases. In the case of a negative test, however, the authors think is necessary also to determine the L/S ratio.
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