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  • Title: Changes in nuclear basic proteins during pseudorabies virus infection.
    Author: Stevens JG, Kado-Boll GJ, Haven CB.
    Journal: J Virol; 1969 May; 3(5):490-7. PubMed ID: 5786178.
    Abstract:
    As a preliminary study to investigation of the possible role played by basic proteins in the genetic regulation of virus-infected cells, acid-extractable proteins synthesized during pseudorabies virus infection were investigated. The synthesis of histones was found to decrease in a gradual manner, and arrest was complete by 6 hr after infection. Five virus-induced acid-extractable proteins appeared in nuclei of infected cells after 4 hr of infection. Four of these proteins were virus structural proteins; one was not. All these proteins contained tryptophan and, therefore, were not "classic" histones.
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