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  • Title: Correlation between growth inhibition and the binding of various penicillins and cephalosporins to Staphylococcus aureus.
    Author: Edwards JR, Park JT.
    Journal: J Bacteriol; 1969 Aug; 99(2):459-62. PubMed ID: 5808073.
    Abstract:
    The concentration of penicillin (or cephalosporin) required to achieve a given rate of binding to Staphylococcus aureus H correlates well with that required for inhibition of growth. This result suggests that the irreversible binding of penicillins and cephalosporins to cells is responsible for their biological activity.
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