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  • Title: Quantitation of radio-labelled vitamin K1 and vitamin K1 epoxide in plasma by high pressure liquid chromatography.
    Author: Bjornsson TD, Swezey SE, Meffin PJ, Blaschke TF.
    Journal: Thromb Haemost; 1978 Apr 30; 39(2):466-73. PubMed ID: 580994.
    Abstract:
    A convenient, accurate and reproducible high pressure liquid chromatographic method for the quantitation of radio-labelled vitamin K1 and vitamin K1 epoxide in plasma is described. The method involves the determination of total ether extractable radioactivity, and a chromatographic separation to determin the relative quantities of radio-labelled vitamin K1 and vitamin K1 epoxide. The method is useful over a wide range of ratios of the two compounds, and has a coeffcient of variation of approximately 5%.
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