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  • Title: Behaviour of murine lymphosarcoma cells during prolonged cultivation in vivo.
    Author: Jurásková V, Drásil V.
    Journal: Folia Biol (Praha); 1978; 24(4):253-63. PubMed ID: 581277.
    Abstract:
    Transplantable strain of murine lymphosarcoma growing as a free suspension in the peritoneal cavity of isologous hosts was isolated after fractionated irradiation of C57BL mice. A 14-year cultivation led to changes in its properties; the mean survival time of the hosts was shortened, the modal number of chromosomes changed from 41--42 to 39 and their radioresistance increased slightly. Strain specificity remained unchanged.
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