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  • Title: [Lithium: EEG, performance and mood under subchronic therapy (author's transl)].
    Author: Herrmann WM, Hamann S, Fichte K, Müller-Oerlinghausen B.
    Journal: Arzneimittelforschung; 1978; 28(9):1520-1. PubMed ID: 582550.
    Abstract:
    In a controlled double-blind trial 2X12 healthy male volunteers were tested during treatment with lithium sulphate (24--36 mval/d) or placebo. Volunteers were tested after one and two weeks' drug intake using the following tests: Quantitative pharmaco EEG, psychological performance and mood scales. In comparison to pacebo, lithium shows increased mistake duration of the pursuit rotor (MLS), decreased flicker fusion threshold and an impairment of mood. The EEG effects (decrease 7--9 cps, increase 20--50 cps) require further clarification.
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