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  • Title: Ophthalmopathy after neck irradiation therapy for Hodgkin's disease.
    Author: Jackson R, Rosenberg C, Kleinmann R, Vagenakis AG, Braverman LE.
    Journal: Cancer Treat Rep; 1979 Aug; 63(8):1393-5. PubMed ID: 582577.
    Abstract:
    Ophthalmopathy associated with autoimmune thyroid disease (Graves' ophthalmopathy) may occur years after irradiation of the neck for nonthyroid malignant disease. Two patients developed this complication 2 and 18 years after irradiation treatment of Hodgkin's disease: one with hypothyroidism associated with Hashimoto's thyroiditis and the other with hyperthyroidism. Careful long-term observation of thyroid function following neck irradiation is recommended in view of this unusual complication and the frequent occurrence of hypothyroidism.
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