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  • Title: [Relationship between the phospholipid metabolism of different portions of rat brain and the degree of circulatory disruption in them (following carotid artery ligation)].
    Author: Gasteva SV, Zamuruev ON.
    Journal: Biull Eksp Biol Med; 1977 Nov; 84(11):539-41. PubMed ID: 588727.
    Abstract:
    Bilateral ligation of common carotid arteries in rats caused a considerable reduction of the blood supply and also a marked fall of phospholipids (PL) metabolism in the hemispheres; in the diencephalon and the midbrain it occurred to a lesser degree; there were no alterations in the blood supply or the PL metabolism in the medulla oblongata and the cerebellum. Dependence of the extent of depression of the PL metabolism on the degree of blood supply disturbances varied in different brain regions. Even 5 hours after the ligation of both carotid arteries there was no restoration of blood supply.
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