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  • Title: In vitro response of relaxin-treated rat uterus to prostaglandins and oxytocin.
    Author: Chamley WA, Bagoyo MM, Bryant-Greenwood GD.
    Journal: Prostaglandins; 1977 Oct; 14(4):763-9. PubMed ID: 594378.
    Abstract:
    Paired segments of rat uterus were treated in vitro with relaxin (W1164-3, 150 GPU/mg) until the amplitude of contraction was reduced to at least 50% of the pre-treatment amplitude. Test segments then received 100 ng of either PGE1, PGE2, PGF2alpha or 250 uU of oxytocin. Control segments remained untreated. There was a significant increase in contraction amplitude in response to the spasmogens (P less than 0.05) but no increase was seen in controls.
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