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  • Title: [Penetration of polyene antibiotics into human embryonic kidney tissue cell cultures].
    Author: Kravchenko LS, Sokolov VN, Vaĭnshteĭn VA, Diment AV, Tereshin IM.
    Journal: Antibiotiki; 1977 Dec; 22(12):1113-6. PubMed ID: 596858.
    Abstract:
    Penetration of 14C-amphotericin AM-2 into the cells of the tissue culture of the human embryon kidneys was studied by means of light autoradiography after incubation with the antibiotic. Microscopic examination of the autographs of the cell slices revealed the presence of the radioactive label in the cytoplasm and nucleoplasm of the cells. The revealed intracellular localization of the label was evident of the antibiotic penetration into the cells.
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