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  • Title: [Electron microscopic study of the localization of adenylate cyclase in the small intestinal epithelial cells of rabbits with NAG-infections].
    Author: Shakhlamov VA, Barkhina TG, Liapin MN, Trager RS.
    Journal: Biull Eksp Biol Med; 1977 Dec; 84(12):731-4. PubMed ID: 597613.
    Abstract:
    As found, in NAG-infection primary intensification of adenylate cyclase activity occurred at the apical plasmalemma of the villar cells; then the process spread to the lateral and further to the basal plasmalemma of the enterocytes. At more advanced stages of NAG-infection an increased adenylate cyclase activity was observed in the crypt cells. Thus, with increased duration of the toxin action there was a gradual rise of the enzyme activity, and the epithelial cells of the small intestine in the area of local affection become involved in the pathological process.
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